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Drug development funnel: what I learnt building one from scratch
Thoughts on the cost of failures, the Phase II graveyard, and buying the race rather than the winner
May 10
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Veera M. Rajagopal
24
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ASHG 2024 HIGHLIGHTS
Previewing Notable Talks and Posters
Nov 5, 2024
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Veera M. Rajagopal
17
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Genomes vs Exomes
Whole genome sequencing vs whole exome sequencing: which one is cost-effective for gene discovery?
Oct 6, 2024
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Veera M. Rajagopal
20
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Discovery of a major genetic risk factor for stroke in South Asians
Exome sequencing of 75k Pakistanis identifies a NOTCH3 genetic variant, accounting for 1-2% of strokes in South Asians
Sep 22, 2024
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Veera M. Rajagopal
19
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De novo enhancer creation by a noncoding mutation
Genetic investigation of a cardiac arrhythmia reveals a new noncoding Mendelian disease mechanism
Sep 15, 2024
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Veera M. Rajagopal
16
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Discovery of TMEFF1, a viral restriction factor in the human brain
Exome sequencing of individuals with herpes simplex viral encephalitis identifies a new genetic mechanism through which neurons resist viral infections
Aug 18, 2024
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Veera M. Rajagopal
13
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The Big tau: A new hope for Alzheimer's?
An overlooked tau isoform may hold the key to an effective Alzheimer's drug
Aug 4, 2024
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Veera M. Rajagopal
11
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How a jumping gene shaped the human skin color evolution
Two separate transposition events within ASIP, encoding agouti protein, have influenced the skin color changes during human evolution
Jul 28, 2024
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Veera M. Rajagopal
21
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