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A founder population fills the gap in psychiatric genetics
42,000 Paisa exomes reveal moderate-effect genes that population-scale sequencing missed
Oct 4
•
Veera M. Rajagopal
14
1
September 2026
Discovery to drug: the story of a rare disease
How activin A became the target in fibrodysplasia ossificans progressiva
Sep 12
•
Veera M. Rajagopal
20
5
3
August 2026
A GWAS locus, all the way down
Twenty years after the association, the CD40 locus gives up its causal variant and the cell state it acts in.
Aug 16
•
Veera M. Rajagopal
14
1
2
FNIP1 loss and protection from metabolic diseases
A massive sequencing study identifies a key pathway in energy balance, and a drug target that was on no one's radar.
Aug 7
•
Veera M. Rajagopal
23
3
July 2026
Introducing GWAS Signals, a Weekly Digest of Human Genetics Literature
GWAS Signals is a sister publication to GWAS Stories, powered by an AI-driven workflow
Jul 12
•
Veera M. Rajagopal
9
May 2026
Drug development funnel: what I learnt building one from scratch
Thoughts on the cost of failures, the Phase II graveyard, and buying the race rather than the winner
May 10
•
Veera M. Rajagopal
26
1
November 2024
ASHG 2024 HIGHLIGHTS
Previewing Notable Talks and Posters
Nov 5, 2024
•
Veera M. Rajagopal
17
2
2
October 2024
Genomes vs Exomes
Whole genome sequencing vs whole exome sequencing: which one is cost-effective for gene discovery?
Oct 6, 2024
•
Veera M. Rajagopal
20
3
September 2024
Discovery of a major genetic risk factor for stroke in South Asians
Exome sequencing of 75k Pakistanis identifies a NOTCH3 genetic variant, accounting for 1-2% of strokes in South Asians
Sep 22, 2024
•
Veera M. Rajagopal
19
3
De novo enhancer creation by a noncoding mutation
Genetic investigation of a cardiac arrhythmia reveals a new noncoding Mendelian disease mechanism
Sep 15, 2024
•
Veera M. Rajagopal
16
6
1
August 2024
Discovery of TMEFF1, a viral restriction factor in the human brain
Exome sequencing of individuals with herpes simplex viral encephalitis identifies a new genetic mechanism through which neurons resist viral infections
Aug 18, 2024
•
Veera M. Rajagopal
13
4
The Big tau: A new hope for Alzheimer's?
An overlooked tau isoform may hold the key to an effective Alzheimer's drug
Aug 4, 2024
•
Veera M. Rajagopal
11
3
2
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